Here are the best goals from week #1 November 2010, courtesy of TVGOLO.com.
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| Goal#1 | Marvin Elliott (Bristol City) | vs Middlesbrough |
| Goal#2 | David Villa (Barcelona) | vs Sevilla |
| Goal#3 | Fábio Coentrão (Benfica) | vs Olympique Lyon |
| Goal#4 | Dimitrije Injac (Lech Poznań) | vs Wisła Kraków |
| Goal#5 | Pablo Aimar (Benfica) | vs Paços Ferreira |
| Goal#6 | Mikkel Thygesen (FC Midtjylland) | vs Horsens |
| Goal#7 | Silvestre Varela (FC Porto) | vs Académica Coimbra |
| Goal#8 | Manuel Martínez (Recreativo Huelva) | vs Celta Vigo |
| Goal#9 | Javier Cortés (Pumas UNAM) | vs Querétaro |
| Goal#10 | Tiago (Atlético Madrid) | vs Rosenborg |
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