|Akeem Adams was a part of Trinidad and Tobago's national team at various levels|
Adams had made six appearances for Ferencváros before suffering a heart attack following a match against Újpest in September.
He had been hospitalised since the collapse and had his left leg amputated in October to alleviate circulatory problems.
After losing his left leg, Adams appeared to be making progress with his recovery and was awaiting a heart transplant.
However, his condition worsened last Saturday following a brain hemorrhage, and he passed away while on life support on Monday morning.
"It is with deep sorrow that we announce the death of FTC's player, Akeem Adams," Ferencváros said in a statement on their official website.
"This Saturday, complications arose and the player's body could not cope anymore."
The Trinidad and Tobago Football Association also released a statement following the death of Adams, who earned nine international caps.
It read: "The Trinidad and Tobago Football Association is deeply saddened by the passing of Akeem Adams.
"We would like to extend our deepest condolences and sympathies on behalf of the officials, players and supporters of all our teams to Akeem's family and friends at this sad time.
"Akeem's uncle Ivan Dick and local representative Dion Sosa confirmed that Akeem left us at 12:45pm TT time."
Fellow footballers and former teammates have also shared their condolences via Twitter.
My condolences to the family of Akeem Adams former Trinidadian footballer Died at the age of 22. May your soul rest on peace bro #rastalove— Lovel Palmer (@lovelpalmer7) December 30, 2013
Always a hard-to-accept moment when the football family loses one of its own. RIP Akeem Adams.— Michael Chabala (@MikeChabala) December 30, 2013
Always a hard-to-accept moment when the football family loses one of its own. RIP Akeem Adams. (Courtesy @brent_sancho)— Shaka Hislop (@ShakaHislop) December 30, 2013
Rip Akeem Adams.— Brent Sancho (@brent_sancho) December 30, 2013