Asamoah Gyan missed a last-gasp penalty at the end of extra-time for Ghana before Uruguay won the penalty shoot-out 4-2 to progress to the last four.
Ghana opened the scoring on the stroke of half-time when Sulley Muntari's speculative long-range effort caught Fernando Muslera wrong-footed.
However, Diego Forlán fired a well-struck free-kick 10 minutes after the break to ensure the game went into extra-time.
The Africans should have settled the contest with the last kick of the game when Luis Suárez handled Dominic Adiyiah's goalbound header on the line, actions that saw him red-carded.
But Gyan missed the chance to become the hero of a nation when he smacked the resultant penalty against the crossbar.
In the penalty shoot-out, John Mensah and Adiyiah had their efforts saved as Uruguay won 4-2 to set up a semi-final clash with the Netherlands in Cape Town on Tuesday.
Lineups:
Uruguay: Fernando Muslera; Maximiliano Pereira, Diego Lugano (Andrés Scotti, 38), Mauricio Victorino, Jorge Fucile; Álvaro Fernández (Nicolás Lodeiro, 46), Diego Pérez, Egidio Arévalo, Edinson Cavani (Sebastián Abreu, 76); Luis Suárez, Diego Forlán
Ghana: Richard Kingson; John Paintsil, Isaac Vorsah, John Mensah, Hans Sarpei; Anthony Annan; Samuel Inkoom (Stephen Appiah, 74), Kwadwo Asamoah, Kevin-Prince Boateng, Sulley Muntari (Dominic Adiyiah, 88); Asamoah Gyan
Penalty Shoot-Out:
Statistics:
Also see:
Ghana opened the scoring on the stroke of half-time when Sulley Muntari's speculative long-range effort caught Fernando Muslera wrong-footed.
However, Diego Forlán fired a well-struck free-kick 10 minutes after the break to ensure the game went into extra-time.
The Africans should have settled the contest with the last kick of the game when Luis Suárez handled Dominic Adiyiah's goalbound header on the line, actions that saw him red-carded.
But Gyan missed the chance to become the hero of a nation when he smacked the resultant penalty against the crossbar.
In the penalty shoot-out, John Mensah and Adiyiah had their efforts saved as Uruguay won 4-2 to set up a semi-final clash with the Netherlands in Cape Town on Tuesday.
Lineups:
Uruguay: Fernando Muslera; Maximiliano Pereira, Diego Lugano (Andrés Scotti, 38), Mauricio Victorino, Jorge Fucile; Álvaro Fernández (Nicolás Lodeiro, 46), Diego Pérez, Egidio Arévalo, Edinson Cavani (Sebastián Abreu, 76); Luis Suárez, Diego Forlán
Ghana: Richard Kingson; John Paintsil, Isaac Vorsah, John Mensah, Hans Sarpei; Anthony Annan; Samuel Inkoom (Stephen Appiah, 74), Kwadwo Asamoah, Kevin-Prince Boateng, Sulley Muntari (Dominic Adiyiah, 88); Asamoah Gyan
Penalty Shoot-Out:
| Paraguay | Japan | |
| Diego Forlán | 1 - 1 | Asamoah Gyan |
| Mauricio Victorino | 2 - 2 | Stephen Appiah |
| Andrés Scotti | 3 - 2 | John Mensah |
| Maximiliano Pereira | 3 - 2 | Dominic Adiyiah |
| Sebastián Abreu | 4 - 2 |
Statistics:
| Uruguay | Ghana | |
| 1 | Goals | 1 |
| 10 | Shots on target | 7 |
| 6 | Shots off target | 13 |
| 12 | Corners | 8 |
| 20 | Fouls | 24 |
| 6 | Offsides | 1 |
| 3 | Yellow Cards | 3 |
| 1 | Red Cards | 0 |
| 49 | Ball possession (%) | 51 |
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Also see:
- World Cup 2010 Second Round: USA 1-2 Ghana
- World Cup 2010 Second Round: Uruguay 2-1 South Korea
- World Cup 2010 Group D: Ghana 0-1 Germany
- World Cup 2010 Group A: Mexico 0-1 Uruguay
- World Cup 2010 Group D: Ghana 1-1 Australia
- World Cup 2010 Group A: South Africa 0-3 Uruguay
- World Cup 2010 Group D: Serbia 0-1 Ghana
- World Cup 2010 Group A: France 0-0 Uruguay
