Here are the best goals from week #3 November 2010, courtesy of TVGOLO.com.
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| Goal#1 | Christian Giménez (Cruz Azul) | vs Pumas UNAM |
| Goal#2 | Lionel Messi (Barcelona) | vs Villarreal |
| Goal#3 | Éder Luís (Vasco da Gama) | vs São Paulo |
| Goal#4 | Nedum Onuoha (Sunderland) | vs Chelsea |
| Goal#5 | Vincenzo Iaquinta (Juventus) | vs AS Roma |
| Goal#6 | Dale Jennings (Tranmere Rovers) | vs Plymouth Argyle |
| Goal#7 | Aleksandar Vuković (Korona Kielce) | vs Jagiellonia Białystok |
| Goal#8 | Tino Costa (Valencia) | vs Getafe |
| Goal#9 | Luís Ramírez (Peru) | vs Colombia |
| Goal#10 | Johan Elmander (Bolton Wanderers) | vs Wolverhampton Wanderers |
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