Here are the best goals from week #3 December 2010, courtesy of TVGOLO.com.
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| Goal#1 | Júlio César (Gaziantepspor) | vs Kayserispor |
| Goal#2 | Lionel Messi (Barcelona) | vs Real Sociedad |
| Goal#3 | Alessandro Rosina (Zenit St Petersburg) | vs AEK Athens |
| Goal#4 | Pablo Piatti (Almería) | vs Sevilla |
| Goal#5 | Cristiano Ronaldo (Real Madrid) | vs Real Zaragoza |
| Goal#6 | Antonio Di Natale (Udinese) | vs Fiorentina |
| Goal#7 | Ricardo Faty (Aris Thessaloniki) | vs Rosenborg |
| Goal#8 | Jonny Hayes (Inverness Caledonian Thistle) | vs Glasgow Rangers |
| Goal#9 | Ricardo Quaresma (Beşiktaş) | vs Rapid Vienna |
| Goal#10 | Lionel Messi (Barcelona) | vs Real Sociedad |
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