Here are the best goals from week #3 September 2010, courtesy of TVGOLO.com.
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| Goal#1 | Tino Costa (Valencia) | vs Bursaspor |
| Goal#2 | Scott Parker (West Ham United) | vs Chelsea |
| Goal#3 | Dean Cox (Leyton Orient) | vs Huddersfield Town |
| Goal#4 | Douglas (Grêmio) | vs Corinthians |
| Goal#5 | Marouane Chamakh (Arsenal) | vs Sporting Braga |
| Goal#6 | Joãozinho (Levski Sofia) | vs KAA Gent |
| Goal#7 | Rodrigo Lima (Sporting Braga) | vs FC Porto |
| Goal#8 | Emanuel Villa (Cruz Azul) | vs Árabe Unido |
| Goal#9 | Thomas Müller (Bayern Munich) | vs AS Roma |
| Goal#10 | Marcos Flores (Adelaide United) | vs Newcastle Jets |
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