Here are the best goals from week #4 December 2010, courtesy of TVGOLO.com.
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| Goal#1 | Yoric Ravet (Grenoble) | vs Dijon |
| Goal#2 | Sercan Yıldırım (Bursaspor) | vs Gençlerbirliği |
| Goal#3 | Ángel di María (Real Madrid) | vs Sevilla |
| Goal#4 | Wesley Sonck (Lierse) | vs Genk |
| Goal#5 | Tino Costa (Valencia) | vs Real Sociedad |
| Goal#6 | Jonathan de Guzmán (Real Mallorca) | vs Villarreal |
| Goal#7 | Fabio Quagliarella (Juventus) | vs Chievo Verona |
| Goal#8 | Osarimen Ebagua (Varese) | vs Siena |
| Goal#9 | Víctor (FC Cartagena) | vs Las Palmas |
| Goal#10 | Edinson Cavani (Napoli) | vs Lecce |
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