Here are the best goals from week #5 April 2011, courtesy of TVGOLO.com.
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| Goal#1 | Kaká (Real Madrid) | vs Valencia |
| Goal#2 | Ruud Boymans (VVV Venlo) | vs Heerenveen |
| Goal#3 | Jorge Valdivia (Palmeiras) | vs Mirassol |
| Goal#4 | Jay Bothroyd (Cardiff City) | vs Queens Park Rangers |
| Goal#5 | Óscar Cardozo (Benfica) | vs Sporting Braga |
| Goal#6 | Willians (Flamengo) | vs Horizonte |
| Goal#7 | Simon Cox (West Bromwich Albion) | vs Tottenham Hotspur |
| Goal#8 | Siem de Jong (Ajax Amsterdam) | vs Excelsior Rotterdam |
| Goal#9 | Alessandro Carrozza (Varese) | vs Ascoli |
| Goal#10 | Lionel Messi (Barcelona) | vs Real Madrid |
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